Immunology, Metabolic, and Oncology (Sponsor-Ded

Syneos Health® is a leading fully-integrated life sciences services organization built to accelerate customer success. We partner with innovators at every point across the drug development and commercialization continuum, helping them navigate complexity, anticipate change and accelerate progress.

Our Clinical Solutions team members act with a drug development mindset, applying their years of experience and deep expertise to truly understand customer needs and represent those in the solutions we shape.

Whether you join us in a Functional Service Provider partnership or a Full-Service environment, you’ll collaborate with passionate problem solvers, innovating as a team to help our customers achieve their goals. We are agile and driven to deliver – for one another, our customers, and, most importantly, for those in need.

Discover what your 25,000 future colleagues already know:

Why Syneos Health

• We are passionate about developing our people, through career development and progression; supportive and engaged line management; technical and therapeutic area training; peer recognition and total rewards program.
• We are committed to building an inclusive culture – where you can authentically be yourself. Central to this is our purpose – Driven to Deliver – which captures the passion of our colleagues to show up each day and shape solutions that have the ability to dramatically impact someone’s life.
• We are continuously building the company we all want to work for and our customers want to work with. Why? Because we know that when we bring together smart colleagues from across the world, we can shape the future of healthcare, driving impact for customers and defining the pace of patient progress.

Job Responsibilities

Senior Global Project Manager – Immunology, Metabolic, and Oncology

Sponsor-Dedicated - Fully Home Based anywhere in US

About the Role:

Within this sponsor, the Clinical Trial Leader (CTL) serves at the Senior Project Manager level and plays a pivotal leadership role within the Clinical Delivery Team. This position provides strategic global oversight, driving alignment, direction, and accountability across Phase II and III clinical trials conducted worldwide. The CTL ensures precise planning, efficient execution, and high-quality delivery of trials that bring speed and value to patients and investigative sites.

Operating across multi-country, multi-regional trials, the CTL provides strong global project management leadership, ensuring milestones, KPIs, and strategic objectives are met. Therapeutic areas include Immunology, Metabolic, and Oncology. Candidates must have extensive Project Management experience leading Phase II & III trials globally, with proven ability to influence and guide diverse teams.

What You Will Do:

Global Trial Preparation

• Lead global planning activities and operational feasibility assessments, ensuring timelines and strategies are realistic and globally aligned.

• Strengthen cross-functional cohesion by working onsite with colleagues in Statistics, Data Management, Medical Writing, Site Monitoring, Quality, and Regulatory.

• Guide country allocation and feasibility processes, helping shape global site strategies with operational insight.

• Develop robust global engagement, recruitment, and risk mitigation plans informed by patient, site, and regional feedback.

• Lead vendor outsourcing strategy—identification, evaluation, and scope-of-work development—ensuring global operational readiness.

• Bring teams together onsite to harmonize trial processes across clinical quality, safety, investigational product management, and financial planning.

• Prepare or support responses to regulatory and ethics authorities across regions.

• Ensure global teams are trained, aligned, and equipped for execution.

Global Trial Conduct

• Maintain high-level oversight of worldwide trial operations, ensuring compliance with GCP, SOPs, and diverse regional regulations.

• Monitor global patient recruitment, risks, timelines, and budgets, driving issue resolution through clear leadership.

• Direct documentation changes, study amendments, and retraining across all regions and functions.

• Provide strong oversight of global vendors, central labs, and external partners, ensuring consistent performance.

• Serve as the connective tissue across global clinical delivery, fostering open communication and unity of purpose.

• Coordinate biomarker, genomic, and sub-study activities for applicable early-phase trials, often requiring cross-regional alignment.

Trial Closeout & Reporting

• Provide global leadership through data cleaning, database lock, and closeout activities.

• Support CTR development and ensure timely global registry disclosure.

• Ensure completeness and accuracy of the Trial Master File (TMF) across all participating regions.

• Support scientific publications and global communication of study outcomes.

Strategic Contributions

• Partner with portfolio leaders to provide operational and scientific insight that shapes global study strategy.

• Elevate risks, bottlenecks, and insights to the Evidence Team to drive swift, coordinated solutions.

• Lead or contribute to global feasibility assessments that influence trial design, operational models, and regional planning.

What You Will Bring:

Required

• Bachelor’s degree (4-year undergraduate degree).

• Proven experience providing global leadership across Phase II & III clinical trials.

• Therapeutic area experience in Immunology, Metabolic, or Oncology.

• Deep understanding of global clinical trial planning, execution, and regulatory landscapes.

• Exceptional leadership, communication, and stakeholder management skills across complex, matrixed, multicultural environments.

• Ability to lead through influence, anticipate global challenges, and ensure patient-focused outcomes.

Core Competencies

• Global Leadership: Confidently guide teams across regions, cultures, and functions; set vision, instill accountability, and shape high-performing global execution.

• Strategic Mindset: Think several steps ahead, anticipate challenges, and align global strategies with portfolio needs.

• Project Management Excellence: Expert in global timelines, risk mitigation, cross-functional coordination, issue escalation, and solution delivery.

• Collaboration & Influence: Build trust across continents; unify teams through clear direction and inspiring presence onsite.

• High-Impact Communication: Transparent, diplomatic, and culturally attuned communicator who elevates team performance.

Why Join This Team:

This is not a traditional project management role — it is a chance to be at the center of global clinical delivery. As a Senior Global Project Manager / Clinical Trial Leader, you will be a visible, influential leader driving the success of trials that span continents. The hybrid model gives you the best of both worlds: meaningful onsite collaboration that strengthens team cohesion, paired with the flexibility of remote work.

You will shape strategy, drive execution, and help deliver therapies that change lives. Your leadership will connect people, processes, and science — ensuring trials advance efficiently, ethically, and with global impact.

At  Syneos Health, we believe in providing an environment and culture in which Our People can thrive, develop and advance. We reward and recognize our people by providing valuable benefits and a quality-of-life balance. The benefits for this position may include a company car or car allowance, Health benefits to include Medical, Dental and Vision, Company match 401k, eligibility to participate in Employee Stock Purchase Plan, Eligibility to earn commissions/bonus based on company and individual performance, and flexible paid time off (PTO) and sick time. Because certain states and municipalities have regulated paid sick time requirements, eligibility for paid sick time may vary depending on where you work. Syneos complies with all applicable federal, state, and municipal paid sick time requirements.

Salary Range:

The base salary range represents the anticipated low and high of the Syneos Health range for this position. Actual salary will vary based on various factors such as the candidate’s qualifications, skills, competencies, and proficiency for the role.

Get to know Syneos Health

Over the past 5 years, we have worked with 94% of all Novel FDA Approved Drugs, 95% of EMA Authorized Products and over 200 Studies across 73,000 Sites and 675,000+ Trial patients.

No matter what your role is, you’ll take the initiative and challenge the status quo with us in a highly competitive and ever-changing environment. Learn more about Syneos Health.

Additional Information

Tasks, duties, and responsibilities as listed in this job description are not exhaustive. The Company, at its sole discretion and with no prior notice, may assign other tasks, duties, and job responsibilities. Equivalent experience, skills, and/or education will also be considered so qualifications of incumbents may differ from those listed in the Job Description. The Company, at its sole discretion, will determine what constitutes as equivalent to the qualifications described above. Further, nothing contained herein should be construed to create an employment contract. Occasionally, required skills/experiences for jobs are expressed in brief terms. Any language contained herein is intended to fully comply with all obligations imposed by the legislation of each country in which it operates, including the implementation of the EU Equality Directive, in relation to the recruitment and employment of its employees. The Company is committed to compliance with the Americans with Disabilities Act, including the provision of reasonable accommodations, when appropriate, to assist employees or applicants to perform the essential functions of the job.

Originally posted on Himalayas